Endocrine Abstracts

Symptomatic pituitary metastasis is an uncommon presentation of primary carcinoma. We report a case of a 65 years old lady who presented with a six week history of headache and diplopia and a five day history of diarrhoea and vomiting. She also suffered from osteoporosis. She had undergone a hysterectomy for a fibroid. Examination revealed diplopia in all directions of gaze, no papilloedema and an unremarkable systemic examination. Brain MRI showed a contrast enhancing pituita...

Background: Preterm infants represent around 10% of births worldwide and have increased risk of adverse metabolic outcomes in later life. The approach to feeding preterms must balance the need to promote brain growth by providing adequate nutrients whilst avoiding potentially harmful excess nutrition.Objective: To investigate the association between patterns of weight gain in infancy and childhood with later insulin sensitivity in adolescents who were bo...

Introduction: Anti-TSH-receptor binding antibodies can cross the placenta and can stimulate or inhibit the fetal thyroid, causing fetal and neonatal thyroid dysfunction. We test for these antibodies in all pregnant women with a history of thyroid disease using a TSH binding inhibitor immunoglobulin (TBII) assay. Our aims were to audit our management of TBII positive pregnancies and to review pregnancy outcomes.Methods: Serum TBII concentration was measur...